Basic Information
Symbol
circEPS15
RNA Class
circRNA
Alias
Epidermal Growth Factor Receptor Pathway Substrate 15
AF-1P
MLLT5
Epidermal Growth Factor Receptor Substrate 15
Protein AF-1p
AF1P
ALL1 Fused Gene From Chromosome 1
Protein Eps15
Location (GRCh37)
1:51820617-51984995
UCSC Genome Browser
Location (GRCh38)
1:51354945-51519323
Host gene
EPS15
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_EPS15_0025600 | Intron-Intron | chr1:51975682-51975853 | chr1:51510010-51510181 | 172 nt | 0.3256 |
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Forensic Context
A study in human traumatic brain injury (TBI) patients demonstrated that the circEPS15 was significantly upregulated in brain injury tissues compared to adjacent contusion tissues, with a fold change of 22.43, and its expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].