Basic Information
Symbol
circESR1
RNA Class
circRNA
Alias
Estrogen Receptor 1
ER-Alpha
NR3A1
ER
Nuclear Receptor Subfamily 3 Group A Member 1
Estradiol Receptor
Era
ESR
Oestrogen Receptor Alpha
E2 Receptor Alpha
Estrogen Receptor
Estrogen Receptor Alpha E1-N2-E2-1-2
Estrogen Receptor Alpha E1-E2-1-2
Estrogen Nuclear Receptor Alpha
Estrogen Receptor Alpha
ESTRR
ESRA
Location (GRCh37)
6:151914242-152442764
UCSC Genome Browser
Location (GRCh38)
6:151593107-152121629
Host gene
ESR1
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification
Time since deposition estimation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ESR1_0001600 | Exon-Exon | chr6:152128454-152201906 | chr6:151807319-151880771 | 1021 nt | 0.6072 |
| hsa_ESR1_0004400 | Exon-Exon | chr6:152201790-152265643 | chr6:151880655-151944508 | 453 nt | 0.5408 |
| hsa_CCDC170_0003000 | Exon-Intergenic | chr6:151914242-151987583 | chr6:151593107-151666448 | 250 nt | 0.3560 |
| hsa_CCDC170_0003200 | Exon-Intergenic | chr6:151914242-152023140 | chr6:151593107-151702005 | 174 nt | 0.4598 |
| hsa_ESR1_0000200 | Intergenic-Exon | chr6:151947495-152023140 | chr6:151626360-151702005 | 139 nt | 0.5612 |
| hsa_ESR1_0000300 | Intergenic-Exon | chr6:151971147-152023140 | chr6:151650012-151702005 | 250 nt | 0.3280 |
| hsa_ESR1_0000400 | Intergenic-Exon | chr6:151972832-152023140 | chr6:151651697-151702005 | 231 nt | 0.3983 |
| hsa_ESR1_0000500 | Intron-Intron | chr6:151986397-151986806 | chr6:151665262-151665671 | 410 nt | 0.4488 |
| hsa_ESR1_0000600 | Intron-Intron | chr6:152005330-152005474 | chr6:151684195-151684339 | 145 nt | 0.5103 |
| hsa_ESR1_0000700 | Intergenic-Exon | chr6:152008724-152023140 | chr6:151687589-151702005 | 250 nt | 0.3520 |
Showing 1 to 10 of 87 entries
Forensic Context
A study in humans demonstrated that the circular RNA (circRNA) form of the circESR1 is expressed in vaginal secretions and menstrual blood, with its detection not impairing specificity for vaginal fluid identification [Liu et al. DOI:10.1007/s00414-019-02027-y]. In a subsequent multiplex assay, the circRNA form of the circESR1 was detected in 36 out of 40 vaginal secretion samples and was confirmed to be RNase R-resistant, indicating its utility for identifying aged biological stains [Liu et al. DOI:10.1016/J.Fsigen.2020.102312].