Basic Information
Symbol
circFAM114A2
RNA Class
circRNA
Alias
Family With Sequence Similarity 114 Member A2
133K02
C5orf3
Protein FAM114A2
Family With Sequence Similarity 114, Member A2
Testis Tissue Sperm-Binding Protein Li 81P
Chromosome 5 Open Reading Frame 3
Location (GRCh37)
5:153413351-153414527
UCSC Genome Browser
Location (GRCh38)
5:154033791-154034967
Host gene
FAM114A2
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
Cause of death analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FAM114A2_0004700 | Exon-Exon | chr5:153413351-153414527 | chr5:154033791-154034967 | 417 nt | 0.4652 |
Forensic Context
A study in human coronary artery segments from an autopsy case demonstrated that hsa_circ_0016868, hsa_circ_0001364, and hsa_circ_0006731 were validated by qRT-PCR and Sanger sequencing, with their expression levels significantly subtler in various coronary artery segments compared to the left main trunk, suggesting a pathological role in coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552]. The literature indicates circFAM114A2 is downregulated in gastric cancer tissues [Lee et al. DOI:10.1016/j.biopha.2018.12.052].