Basic Information

Symbol
circFBXW7
RNA Class
circRNA
Alias
F-Box And WD Repeat Domain Containing 7 SEL-10 SEL10 FBX30 FBW7 FBXW6 CDC4 AGO F-Box And WD Repeat Domain Containing 7, E3 Ubiquitin Protein Ligase F-Box And WD-40 Domain Protein 7 (Archipelago Homolog, Drosophila) F-Box/WD Repeat-Containing Protein 7 F-Box Protein FBX30 FLJ11071 HCdc4 HAgo F-Box And WD-40 Domain-Containing Protein 7 Archipelago Homolog (Drosophila) Homolog Of C Elegans Sel-10 F-Box Protein SEL-10 Archipelago Homolog F-Box Protein FBW7 Archipelago DEDHIL FBXO30 FBW6
Location (GRCh37)
4:153243748-153456566 UCSC Genome Browser
Location (GRCh38)
4:152322596-152535414
UCSC Genome Browser Search in Marker Scope
Host gene
FBXW7
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FBXW7_0004800 Intron-Intron chr4:153280364-153280609 chr4:152359212-152359457 246 nt 0.4431
hsa_FBXW7_0004900 Intron-Exon-Intron chr4:153280610-153333681 chr4:152359458-152412529 620 nt 0.4548
hsa_FBXW7_0005000 Intron-Intron chr4:153293697-153293877 chr4:152372545-152372725 181 nt 0.3315
hsa_chr4_0190700 Intergenic-Intergenic chr4:153297708-153298263 chr4:152376556-152377111 556 nt 0.3345
hsa_FBXW7_0005100 Intron-Exon chr4:153298325-153303518 chr4:152377173-152382366 250 nt 0.3320
hsa_FBXW7_0005200 Intron-Exon-Intron chr4:153298325-153333681 chr4:152377173-152412529 50 nt 0.4600
hsa_FBXW7_0005300 Intron-Exon-Intron chr4:153298325-153403825 chr4:152377173-152482673 402 nt 0.3781
hsa_FBXW7_0005400 Intron-Intron chr4:153301936-153302242 chr4:152380784-152381090 307 nt 0.2899
hsa_FBXW7_0005700 Intron-Intron chr4:153303341-153308410 chr4:152382189-152387258 271 nt 0.3838
hsa_FBXW7_0005800 Intron-Exon chr4:153303341-153333024 chr4:152382189-152411872 238 nt 0.4790
Showing 61 to 70 of 163 entries
Forensic Context

A study in human brain cancer demonstrated that the circFBXW7 functions as a tumor suppressor, where its expression inhibits cell progression, migration, and tumor formation [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. Further research confirmed its coding potential, showing the translated peptide FBXW7-185aa reduces the half-life of c-Myc and inhibits cell cycle progression [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. The peptide FBXW7-185aa, which originates from the circFBXW7, inhibits cell cycle progression [Misir et al. DOI:10.1038/s41418-022-00948-7].