Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FGD4_0003400 | Exon-Exon | chr12:32729200-32755251 | chr12:32576266-32602317 | 1185 nt | 0.4321 |
| hsa_FGD4_0003000 | Exon-Exon | chr12:32729200-32764217 | chr12:32576266-32611283 | 1430 nt | 0.4280 |
| hsa_FGD4_0004500 | Exon-Exon | chr12:32734894-32755251 | chr12:32581960-32602317 | 1001 nt | 0.4286 |
| hsa_FGD4_0004700 | Exon-Exon | chr12:32734894-32764217 | chr12:32581960-32611283 | 1346 nt | 0.4198 |
| hsa_FGD4_0004800 | Exon-Exon | chr12:32734894-32772804 | chr12:32581960-32619870 | 1519 nt | 0.4213 |
| hsa_FGD4_0005100 | Exon-Exon | chr12:32734894-32778713 | chr12:32581960-32625779 | 1769 nt | 0.4211 |
| hsa_FGD4_0005200 | Exon-Exon | chr12:32734894-32786623 | chr12:32581960-32633689 | 1910 nt | 0.4157 |
| hsa_FGD4_0006800 | Intron-Exon-Intron | chr12:32749558-32764217 | chr12:32596624-32611283 | 2611 nt | 0.3845 |
| hsa_FGD4_0007400 | Exon-Exon | chr12:32751431-32754268 | chr12:32598497-32601334 | 247 nt | 0.3846 |
| hsa_FGD4_0007500 | Exon-Exon | chr12:32751431-32754357 | chr12:32598497-32601423 | 336 nt | 0.3720 |
Showing 1 to 10 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].