Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FGD4_0006200 | Intron-Exon-Intron | chr12:32743475-32778002 | chr12:32590541-32625068 | 124 nt | 0.4032 |
| hsa_FGD4_0006000 | Intron-Exon-Intron | chr12:32743475-32778713 | chr12:32590541-32625779 | 250 nt | 0.3480 |
| hsa_FGD4_0006100 | Intron-Exon-Intron | chr12:32743475-32786623 | chr12:32590541-32633689 | 250 nt | 0.3120 |
| hsa_FGD4_0006300 | Intron-Exon-Intron | chr12:32745899-32772804 | chr12:32592965-32619870 | 250 nt | 0.3040 |
| hsa_FGD4_0006500 | Intron-Exon-Intron | chr12:32747150-32764217 | chr12:32594216-32611283 | 153 nt | 0.3856 |
| hsa_FGD4_0006400 | Intron-Exon-Intron | chr12:32747150-32772804 | chr12:32594216-32619870 | 250 nt | 0.3640 |
| hsa_FGD4_0006600 | Intron-Exon-Intron | chr12:32747150-32778713 | chr12:32594216-32625779 | 126 nt | 0.4365 |
| hsa_FGD4_0006700 | Intron-Exon-Intron | chr12:32749538-32772804 | chr12:32596604-32619870 | 2804 nt | 0.3862 |
| hsa_FGD4_0006900 | Intron-Exon-Intron | chr12:32750837-32751520 | chr12:32597903-32598586 | 684 nt | 0.3889 |
| hsa_FGD4_0007700 | Exon-Exon | chr12:32751431-32761029 | chr12:32598497-32608095 | 145 nt | 0.4483 |
Showing 101 to 110 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].