Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr12_0311100 | Intergenic-Intergenic | chr12:32769288-32769504 | chr12:32616354-32616570 | 217 nt | 0.4516 |
| hsa_chr12_0311200 | Intergenic-Intergenic | chr12:32771149-32793444 | chr12:32618215-32640510 | 250 nt | 0.3920 |
| hsa_FGD4_0012400 | Exon-Exon | chr12:32772632-32778713 | chr12:32619698-32625779 | 392 nt | 0.4260 |
| hsa_FGD4_0012500 | Exon-Exon | chr12:32772632-32791729 | chr12:32619698-32638795 | 1004 nt | 0.4512 |
| hsa_FGD4_0012600 | Exon-Exon | chr12:32772632-32793387 | chr12:32619698-32640453 | 1182 nt | 0.4628 |
| hsa_chr12_0311300 | Intergenic-Intergenic | chr12:32772700-32793530 | chr12:32619766-32640596 | 1257 nt | 0.4694 |
| hsa_FGD4_0012700 | Exon-Exon | chr12:32772767-32778713 | chr12:32619833-32625779 | 381 nt | 0.4698 |
| hsa_FGD4_0012800 | Exon-Exon | chr12:32772767-32793387 | chr12:32619833-32640453 | 131 nt | 0.4427 |
| hsa_chr12_0311400 | Intergenic-Intergenic | chr12:32773746-32774048 | chr12:32620812-32621114 | 303 nt | 0.4851 |
| hsa_chr12_0311500 | Intergenic-Intergenic | chr12:32776480-32776777 | chr12:32623546-32623843 | 298 nt | 0.4094 |
Showing 141 to 150 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].