Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FGD4_0012900 | Exon-Exon | chr12:32777356-32778713 | chr12:32624422-32625779 | 250 nt | 0.4200 |
| hsa_FGD4_0013000 | Exon-Exon | chr12:32777356-32786623 | chr12:32624422-32633689 | 172 nt | 0.3605 |
| hsa_FGD4_0013100 | Exon-Exon | chr12:32777910-32778713 | chr12:32624976-32625779 | 219 nt | 0.4201 |
| hsa_FGD4_0013200 | Exon-Exon | chr12:32777910-32786623 | chr12:32624976-32633689 | 99 nt | 0.3939 |
| hsa_FGD4_0013300 | Exon-Exon | chr12:32778588-32786623 | chr12:32625654-32633689 | 267 nt | 0.3895 |
| hsa_FGD4_0013400 | Exon-Exon | chr12:32791589-32791729 | chr12:32638655-32638795 | 141 nt | 0.4752 |
| hsa_FGD4_0013500 | Exon-Exon | chr12:32793497-32793798 | chr12:32640563-32640864 | 302 nt | 0.3543 |
| hsa_FGD4_0013600 | Exon-Exon | chr12:32793762-32794160 | chr12:32640828-32641226 | 399 nt | 0.2807 |
| hsa_chr12_0311600 | Intergenic-Intergenic | chr12:32793825-32794554 | chr12:32640891-32641620 | 730 nt | 0.2986 |
| hsa_chr12_0311800 | Intergenic-Intergenic | chr12:32795596-32795858 | chr12:32642662-32642924 | 263 nt | 0.3422 |
Showing 151 to 160 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].