Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FGD4_0007600 | Exon-Exon | chr12:32751431-32755251 | chr12:32598497-32602317 | 493 nt | 0.3712 |
| hsa_FGD4_0007000 | Exon-Exon | chr12:32751431-32764217 | chr12:32598497-32611283 | 738 nt | 0.3835 |
| hsa_FGD4_0007900 | Exon-Exon | chr12:32751431-32772804 | chr12:32598497-32619870 | 1011 nt | 0.3897 |
| hsa_FGD4_0007100 | Exon-Exon | chr12:32751431-32777386 | chr12:32598497-32624452 | 942 nt | 0.3938 |
| hsa_FGD4_0008100 | Exon-Exon | chr12:32751431-32778713 | chr12:32598497-32625779 | 1261 nt | 0.3957 |
| hsa_FGD4_0008200 | Exon-Exon | chr12:32751431-32786623 | chr12:32598497-32633689 | 1402 nt | 0.3909 |
| hsa_FGD4_0007200 | Intron-Exon-Intron | chr12:32751431-32791863 | chr12:32598497-32638929 | 1577 nt | 0.4046 |
| hsa_FGD4_0009000 | Exon-Exon | chr12:32754212-32755251 | chr12:32601278-32602317 | 303 nt | 0.3729 |
| hsa_FGD4_0009600 | Exon-Exon | chr12:32755095-32772804 | chr12:32602161-32619870 | 675 nt | 0.3985 |
| hsa_FGD4_0009700 | Exon-Exon | chr12:32755095-32778002 | chr12:32602161-32625068 | 799 nt | 0.3992 |
Showing 11 to 20 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].