Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr12_0309900 | Intergenic-Intergenic | chr12:32629007-32629370 | chr12:32476073-32476436 | 364 nt | 0.3736 |
| hsa_chr12_0310000 | Intergenic-Intergenic | chr12:32629437-32629750 | chr12:32476503-32476816 | 314 nt | 0.4554 |
| hsa_FGD4_0001200 | Intron-Exon-Intron | chr12:32629865-32755251 | chr12:32476931-32602317 | 250 nt | 0.3040 |
| hsa_FGD4_0001300 | Intron-Intron | chr12:32630130-32633190 | chr12:32477196-32480256 | 250 nt | 0.3880 |
| hsa_chr12_0310100 | Intergenic-Intergenic | chr12:32632805-32634668 | chr12:32479871-32481734 | 1864 nt | 0.4785 |
| hsa_chr12_0310200 | Intergenic-Intergenic | chr12:32643487-32648775 | chr12:32490553-32495841 | 250 nt | 0.3960 |
| hsa_FGD4_0001400 | Intron-Exon-Intron | chr12:32646586-32717223 | chr12:32493652-32564289 | 250 nt | 0.3600 |
| hsa_chr12_0310300 | Intergenic-Intergenic | chr12:32649415-32652959 | chr12:32496481-32500025 | 250 nt | 0.3040 |
| hsa_chr12_0310400 | Intergenic-Intergenic | chr12:32652840-32653487 | chr12:32499906-32500553 | 648 nt | 0.3873 |
| hsa_FGD4_0001500 | Intron-Intron | chr12:32652860-32653462 | chr12:32499926-32500528 | 603 nt | 0.3748 |
Showing 51 to 60 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].