Basic Information
Symbol
circFGD4
RNA Class
circRNA
Alias
FYVE, RhoGEF And PH Domain Containing 4
ZFYVE6
FRABP
CMT4H
FYVE, RhoGEF And PH Domain-Containing Protein 4
Zinc Finger FYVE Domain-Containing Protein 6
FGD1-Related F-Actin-Binding Protein
FGD1 Family, Member 4
Frabin
Actin-Filament Binding Protein Frabin
Actin Filament-Binding Protein Frabin
Location (GRCh37)
12:32553594-32797706
UCSC Genome Browser
Location (GRCh38)
12:32400660-32644772
Host gene
FGD4
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FGD4_0001600 | Intron-Intron | chr12:32664119-32665040 | chr12:32511185-32512106 | 63 nt | 0.4444 |
| hsa_chr12_0310600 | Intergenic-Intergenic | chr12:32665639-32665801 | chr12:32512705-32512867 | 163 nt | 0.3681 |
| hsa_chr12_0310700 | Intergenic-Intergenic | chr12:32690912-32692425 | chr12:32537978-32539491 | 1514 nt | 0.4306 |
| hsa_chr12_0310800 | Intergenic-Intergenic | chr12:32691149-32698214 | chr12:32538215-32545280 | 250 nt | 0.2840 |
| hsa_FGD4_0001700 | Intron-Exon-Intron | chr12:32707101-32717223 | chr12:32554167-32564289 | 2982 nt | 0.4252 |
| hsa_FGD4_0001800 | Exon-Exon | chr12:32709808-32717223 | chr12:32556874-32564289 | 275 nt | 0.5200 |
| hsa_FGD4_0001900 | Intron-Exon-Intron | chr12:32712553-32717223 | chr12:32559619-32564289 | 250 nt | 0.3600 |
| hsa_chr12_0310900 | Intergenic-Intergenic | chr12:32713715-32713915 | chr12:32560781-32560981 | 201 nt | 0.4577 |
| hsa_FGD4_0002100 | Exon-Exon | chr12:32717071-32717223 | chr12:32564137-32564289 | 153 nt | 0.4967 |
| hsa_FGD4_0002300 | Exon-Exon | chr12:32717071-32729348 | chr12:32564137-32576414 | 445 nt | 0.4697 |
Showing 61 to 70 of 160 entries
Forensic Context
A study in mice demonstrated that the circFGD4 is highly expressed in the brain and spinal cord, where it functions as a miRNA sponge to regulate neuronal apoptosis and axon regeneration following spinal cord injury [Li et al. DOI:10.1016/j.neulet.2021.135795]. A study in human traumatic brain injury (TBI) patients identified the circFGD4 as a top up-regulated circular RNA (fold change 21.07) in brain injury tissues compared to adjacent contusion tissues, with its expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].