Basic Information

Symbol
circFGGY
RNA Class
circRNA
Alias
FGGY Carbohydrate Kinase Domain Containing FGGY Carbohydrate Kinase Domain-Containing Protein D-Ribulokinase FGGY FLJ10986 D-Ribulokinase EC 2.7.1.47 EC 2.7.1
Location (GRCh37)
1:59787208-59812070 UCSC Genome Browser
Location (GRCh38)
1:59321536-59346398
UCSC Genome Browser Search in Marker Scope
Host gene
FGGY
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FGGY_0004700 Exon-Exon chr1:59787208-59812070 chr1:59321536-59346398 479 nt 0.5136
Forensic Context

A study in humans and Arabidopsis thaliana using the CircCode tool identified 3,610 and 1,569 translated circRNAs, respectively, from ribosome profiling data, demonstrating the tool's high sensitivity and a low false discovery rate of 0.0027 [Sun et al. DOI:10.3389/fgene.2019.00981]. The literature extensively documents that the circFGGY exhibits tissue-specific expression and functions as a critical regulator in cellular processes, with specific circRNAs like ciRS-7/CDR1as being highly abundant in brain tissue and associated with neurological disorders, while circFOXO3 is expressed in peripheral blood of aged individuals and linked to aging and cardiac function [Misir et al. DOI:10.1038/s41418-022-00948-7].