Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0000300 Exon-Exon chr3:171757418-171830380 chr3:172039628-172112590 283 nt 0.6466
hsa_FNDC3B_0000400 Exon-Exon chr3:171757418-171851336 chr3:172039628-172133546 359 nt 0.5961
hsa_FNDC3B_0000500 Exon-Exon chr3:171757418-171905080 chr3:172039628-172187290 250 nt 0.4080
hsa_FNDC3B_0000900 Exon-Exon chr3:171758344-171851336 chr3:172040554-172133546 286 nt 0.5594
hsa_FNDC3B_0001000 Exon-Exon chr3:171758344-171944737 chr3:172040554-172226947 363 nt 0.5455
hsa_FNDC3B_0001100 Exon-Exon chr3:171758344-171965566 chr3:172040554-172247776 607 nt 0.5338
hsa_FNDC3B_0001200 Exon-Exon chr3:171758344-171969331 chr3:172040554-172251541 889 nt 0.5219
hsa_FNDC3B_0005800 Intron-Intron chr3:171820082-171820229 chr3:172102292-172102439 148 nt 0.4392
hsa_FNDC3B_0006400 Exon-Exon chr3:171830242-171830380 chr3:172112452-172112590 139 nt 0.5180
hsa_FNDC3B_0006500 Exon-Exon chr3:171830242-171851336 chr3:172112452-172133546 215 nt 0.4791
Showing 1 to 10 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].