Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0003000 Intron-Intron chr3:171781394-171782329 chr3:172063604-172064539 936 nt 0.4252
hsa_FNDC3B_0003100 Intron-Exon-Intron chr3:171784093-171851336 chr3:172066303-172133546 76 nt 0.4079
hsa_FNDC3B_0003200 Intron-Intron chr3:171791756-171792830 chr3:172073966-172075040 1075 nt 0.4028
hsa_chr3_0365400 Intergenic-Intergenic chr3:171792587-171794000 chr3:172074797-172076210 1414 nt 0.3663
hsa_FNDC3B_0003300 Intron-Exon-Intron chr3:171796537-171830380 chr3:172078747-172112590 250 nt 0.4000
hsa_FNDC3B_0003400 Intron-Exon-Intron chr3:171796537-171969331 chr3:172078747-172251541 250 nt 0.4080
hsa_FNDC3B_0003500 Intron-Exon-Intron chr3:171796651-171830380 chr3:172078861-172112590 250 nt 0.3800
hsa_FNDC3B_0003800 Intron-Intron chr3:171797144-171799189 chr3:172079354-172081399 219 nt 0.4201
hsa_FNDC3B_0003600 Intron-Intron chr3:171797144-171799505 chr3:172079354-172081715 2362 nt 0.3810
hsa_FNDC3B_0003900 Intron-Exon chr3:171797144-171830335 chr3:172079354-172112545 94 nt 0.5000
Showing 91 to 100 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].