Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FNDC3B_0004000 | Intron-Exon-Intron | chr3:171797144-171830380 | chr3:172079354-172112590 | 176 nt | 0.4830 |
| hsa_FNDC3B_0004100 | Intron-Exon-Intron | chr3:171797144-171851336 | chr3:172079354-172133546 | 434 nt | 0.4493 |
| hsa_FNDC3B_0003700 | Intron-Exon-Intron | chr3:171797144-171944737 | chr3:172079354-172226947 | 250 nt | 0.3800 |
| hsa_FNDC3B_0004200 | Intron-Exon-Intron | chr3:171797144-171969331 | chr3:172079354-172251541 | 182 nt | 0.4341 |
| hsa_FNDC3B_0004500 | Intron-Intron | chr3:171799153-171799505 | chr3:172081363-172081715 | 353 nt | 0.2861 |
| hsa_FNDC3B_0004600 | Intron-Intron | chr3:171799153-171800670 | chr3:172081363-172082880 | 1518 nt | 0.3564 |
| hsa_FNDC3B_0004700 | Intron-Exon-Intron | chr3:171799153-171830380 | chr3:172081363-172112590 | 176 nt | 0.4830 |
| hsa_FNDC3B_0004300 | Intron-Exon-Intron | chr3:171799153-171840163 | chr3:172081363-172122373 | 250 nt | 0.2920 |
| hsa_FNDC3B_0004800 | Intron-Exon-Intron | chr3:171799153-171851336 | chr3:172081363-172133546 | 43 nt | 0.3488 |
| hsa_FNDC3B_0004900 | Intron-Exon-Intron | chr3:171799153-171876582 | chr3:172081363-172158792 | 252 nt | 0.3492 |
Showing 101 to 110 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].