Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FNDC3B_0005000 | Intron-Exon-Intron | chr3:171799153-171944737 | chr3:172081363-172226947 | 83 nt | 0.4940 |
| hsa_FNDC3B_0005100 | Intron-Exon-Intron | chr3:171799153-171969331 | chr3:172081363-172251541 | 37 nt | 0.3514 |
| hsa_FNDC3B_0004400 | Intron-Exon-Intron | chr3:171799153-171979873 | chr3:172081363-172262083 | 250 nt | 0.2960 |
| hsa_FNDC3B_0005200 | Intron-Intron | chr3:171802755-171803179 | chr3:172084965-172085389 | 425 nt | 0.3553 |
| hsa_FNDC3B_0005300 | Intron-Intron | chr3:171803927-171804079 | chr3:172086137-172086289 | 153 nt | 0.4771 |
| hsa_FNDC3B_0005400 | Intron-Intron | chr3:171805719-171805968 | chr3:172087929-172088178 | 250 nt | 0.3680 |
| hsa_FNDC3B_0005500 | Intron-Intron | chr3:171807112-171808157 | chr3:172089322-172090367 | 1046 nt | 0.3795 |
| hsa_FNDC3B_0005600 | Intron-Exon-Intron | chr3:171814581-171830380 | chr3:172096791-172112590 | 250 nt | 0.3640 |
| hsa_FNDC3B_0005700 | Intron-Exon-Intron | chr3:171814581-171851336 | chr3:172096791-172133546 | 156 nt | 0.3590 |
| hsa_chr3_0365500 | Intergenic-Intergenic | chr3:171817412-171818422 | chr3:172099622-172100632 | 1011 nt | 0.3264 |
Showing 111 to 120 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].