Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr3_0365600 | Intergenic-Intergenic | chr3:171819284-171820010 | chr3:172101494-172102220 | 727 nt | 0.3315 |
| hsa_FNDC3B_0005900 | Intron-Intron | chr3:171821703-171821943 | chr3:172103913-172104153 | 241 nt | 0.3610 |
| hsa_FNDC3B_0006000 | Intron-Intron | chr3:171824585-171824862 | chr3:172106795-172107072 | 278 nt | 0.3921 |
| hsa_FNDC3B_0006100 | Intron-Exon-Intron | chr3:171824797-171830380 | chr3:172107007-172112590 | 250 nt | 0.4240 |
| hsa_FNDC3B_0006200 | Intron-Exon-Intron | chr3:171824797-171851336 | chr3:172107007-172133546 | 250 nt | 0.3880 |
| hsa_FNDC3B_0006300 | Intron-Exon-Intron | chr3:171824797-171944737 | chr3:172107007-172226947 | 77 nt | 0.4935 |
| hsa_chr3_0365700 | Intergenic-Intergenic | chr3:171827784-171828630 | chr3:172109994-172110840 | 847 nt | 0.4534 |
| hsa_FNDC3B_0007400 | Intron-Exon-Intron | chr3:171830242-171833500 | chr3:172112452-172115710 | 250 nt | 0.4040 |
| hsa_FNDC3B_0007500 | Intron-Exon-Intron | chr3:171830242-171840163 | chr3:172112452-172122373 | 250 nt | 0.3560 |
| hsa_FNDC3B_0007600 | Intron-Exon-Intron | chr3:171830242-171863009 | chr3:172112452-172145219 | 250 nt | 0.3480 |
Showing 121 to 130 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].