Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FNDC3B_0007700 | Intron-Exon-Intron | chr3:171830242-171866360 | chr3:172112452-172148570 | 250 nt | 0.3760 |
| hsa_FNDC3B_0007800 | Intron-Exon-Intron | chr3:171830242-171871543 | chr3:172112452-172153753 | 250 nt | 0.3840 |
| hsa_FNDC3B_0008200 | Intron-Exon-Intron | chr3:171830242-171871631 | chr3:172112452-172153841 | 145 nt | 0.5241 |
| hsa_FNDC3B_0008300 | Intron-Exon-Intron | chr3:171830242-171876582 | chr3:172112452-172158792 | 145 nt | 0.4966 |
| hsa_FNDC3B_0008400 | Intron-Exon-Intron | chr3:171830242-171879120 | chr3:172112452-172161330 | 139 nt | 0.5180 |
| hsa_FNDC3B_0008500 | Intron-Exon-Intron | chr3:171830242-171887160 | chr3:172112452-172169370 | 139 nt | 0.5180 |
| hsa_FNDC3B_0007900 | Intron-Exon-Intron | chr3:171830242-171902173 | chr3:172112452-172184383 | 250 nt | 0.3640 |
| hsa_FNDC3B_0008000 | Intron-Exon-Intron | chr3:171830242-171923268 | chr3:172112452-172205478 | 250 nt | 0.3320 |
| hsa_FNDC3B_0008700 | Intron-Exon-Intron | chr3:171830242-171923430 | chr3:172112452-172205640 | 162 nt | 0.4630 |
| hsa_FNDC3B_0008800 | Exon-Exon | chr3:171830242-171965566 | chr3:172112452-172247776 | 244 nt | 0.5164 |
Showing 131 to 140 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].