Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0009800 Intron-Intron chr3:171842992-171843228 chr3:172125202-172125438 237 nt 0.5570
hsa_chr3_0365800 Intergenic-Intergenic chr3:171845603-171845911 chr3:172127813-172128121 309 nt 0.4498
hsa_FNDC3B_0009900 Intron-Intron chr3:171848979-171850398 chr3:172131189-172132608 1420 nt 0.3824
hsa_FNDC3B_0010600 Intron-Exon-Intron chr3:171851261-171871631 chr3:172133471-172153841 76 nt 0.4079
hsa_FNDC3B_0010400 Intron-Exon-Intron chr3:171851261-171876582 chr3:172133471-172158792 250 nt 0.2720
hsa_FNDC3B_0010500 Intron-Exon-Intron chr3:171851261-171879120 chr3:172133471-172161330 250 nt 0.2840
hsa_FNDC3B_0010700 Exon-Exon chr3:171851261-172003774 chr3:172133471-172285984 59 nt 0.4068
hsa_chr3_0365900 Intergenic-Intergenic chr3:171851606-171857907 chr3:172133816-172140117 250 nt 0.3400
hsa_FNDC3B_0010800 Intron-Intron chr3:171851636-171852078 chr3:172133846-172134288 443 nt 0.4537
hsa_FNDC3B_0010900 Intron-Intron chr3:171851826-171852137 chr3:172134036-172134347 312 nt 0.4167
Showing 151 to 160 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].