Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr3_0366000 Intergenic-Intergenic chr3:171854664-171855093 chr3:172136874-172137303 430 nt 0.4349
hsa_chr3_0366100 Intergenic-Intergenic chr3:171855849-171858065 chr3:172138059-172140275 2217 nt 0.3753
hsa_FNDC3B_0011000 Intron-Intron chr3:171856230-171856413 chr3:172138440-172138623 184 nt 0.2446
hsa_FNDC3B_0011100 Intron-Intron chr3:171858436-171858626 chr3:172140646-172140836 191 nt 0.4607
hsa_chr3_0366200 Intergenic-Intergenic chr3:171864026-171864672 chr3:172146236-172146882 647 nt 0.3833
hsa_FNDC3B_0011200 Intron-Intron chr3:171868186-171868772 chr3:172150396-172150982 587 nt 0.3475
hsa_FNDC3B_0011300 Intron-Intron chr3:171871436-171876582 chr3:172153646-172158792 108 nt 0.4537
hsa_FNDC3B_0011400 Intron-Intron chr3:171873656-171876582 chr3:172155866-172158792 176 nt 0.3239
hsa_FNDC3B_0011500 Intron-Intron chr3:171873969-171874996 chr3:172156179-172157206 1028 nt 0.3881
hsa_chr3_0366300 Intergenic-Intergenic chr3:171875375-171875562 chr3:172157585-172157772 188 nt 0.3245
Showing 161 to 170 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].