Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr3_0366400 Intergenic-Intergenic chr3:171876895-171877158 chr3:172159105-172159368 264 nt 0.4962
hsa_FNDC3B_0011600 Intron-Intron chr3:171883078-171891308 chr3:172165288-172173518 250 nt 0.3000
hsa_chr3_0366500 Intergenic-Intergenic chr3:171884201-171884383 chr3:172166411-172166593 183 nt 0.4098
hsa_FNDC3B_0011700 Intron-Intron chr3:171887726-171887882 chr3:172169936-172170092 157 nt 0.3822
hsa_FNDC3B_0011800 Intron-Intron chr3:171889344-171889708 chr3:172171554-172171918 365 nt 0.3918
hsa_chr3_0366600 Intergenic-Intergenic chr3:171889664-171889865 chr3:172171874-172172075 202 nt 0.4010
hsa_FNDC3B_0011900 Intron-Intron chr3:171897180-171897378 chr3:172179390-172179588 199 nt 0.4322
hsa_FNDC3B_0012000 Intron-Intron chr3:171901802-171902148 chr3:172184012-172184358 347 nt 0.3804
hsa_chr3_0366800 Intergenic-Intergenic chr3:171902937-171903186 chr3:172185147-172185396 250 nt 0.3920
hsa_FNDC3B_0012100 Intron-Intron chr3:171906021-171933282 chr3:172188231-172215492 250 nt 0.4280
Showing 171 to 180 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].