Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0008600 Exon-Exon chr3:171830242-171905080 chr3:172112452-172187290 250 nt 0.2920
hsa_FNDC3B_0006600 Exon-Exon chr3:171830242-171944737 chr3:172112452-172226947 292 nt 0.4829
hsa_FNDC3B_0006700 Exon-Exon chr3:171830242-171969331 chr3:172112452-172251541 818 nt 0.4976
hsa_FNDC3B_0006800 Exon-Exon chr3:171830242-172055191 chr3:172112452-172337401 1880 nt 0.4809
hsa_FNDC3B_0006900 Exon-Exon chr3:171830242-172064230 chr3:172112452-172346440 2392 nt 0.4929
hsa_FNDC3B_0007000 Exon-Exon chr3:171830242-172065151 chr3:172112452-172347361 2542 nt 0.4902
hsa_FNDC3B_0007100 Exon-Exon chr3:171830242-172096226 chr3:172112452-172378436 250 nt 0.4160
hsa_FNDC3B_0007200 Exon-Exon chr3:171830242-172098883 chr3:172112452-172381093 250 nt 0.3640
hsa_FNDC3B_0007300 Exon-Exon chr3:171830242-172118492 chr3:172112452-172400702 250 nt 0.3000
hsa_FNDC3B_0010000 Exon-Exon chr3:171851261-171851336 chr3:172133471-172133546 76 nt 0.4079
Showing 11 to 20 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].