Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0013800 Exon-Exon chr3:171944661-172070873 chr3:172226871-172353083 83 nt 0.5060
hsa_FNDC3B_0013200 Exon-Exon chr3:171944661-172080635 chr3:172226871-172362845 2821 nt 0.4942
hsa_FNDC3B_0013900 Exon-Exon chr3:171944661-172098883 chr3:172226871-172381093 321 nt 0.5109
hsa_FNDC3B_0014000 Exon-Exon chr3:171944661-172115282 chr3:172226871-172397492 128 nt 0.4063
hsa_FNDC3B_0014100 Intron-Intron chr3:171944794-171946258 chr3:172227004-172228468 1465 nt 0.3720
hsa_chr3_0366900 Intergenic-Intergenic chr3:171948784-171948957 chr3:172230994-172231167 174 nt 0.3391
hsa_FNDC3B_0014200 Intron-Intron chr3:171949949-171952003 chr3:172232159-172234213 2055 nt 0.3815
hsa_FNDC3B_0014300 Intron-Intron chr3:171951633-171951793 chr3:172233843-172234003 161 nt 0.3602
hsa_FNDC3B_0014400 Intron-Exon-Intron chr3:171953486-171969331 chr3:172235696-172251541 250 nt 0.3760
hsa_FNDC3B_0014500 Intron-Exon-Intron chr3:171954052-171969331 chr3:172236262-172251541 250 nt 0.3840
Showing 191 to 200 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].