Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr3_0367000 | Intergenic-Intergenic | chr3:171955352-171955520 | chr3:172237562-172237730 | 169 nt | 0.3728 |
| hsa_FNDC3B_0014700 | Intron-Intron | chr3:171961625-171962351 | chr3:172243835-172244561 | 727 nt | 0.3604 |
| hsa_FNDC3B_0015800 | Exon-Exon | chr3:171965323-171965566 | chr3:172247533-172247776 | 244 nt | 0.5164 |
| hsa_FNDC3B_0015900 | Intron-Exon-Intron | chr3:171965323-171969482 | chr3:172247533-172251692 | 677 nt | 0.4668 |
| hsa_FNDC3B_0016100 | Intron-Exon-Intron | chr3:171965323-171970480 | chr3:172247533-172252690 | 155 nt | 0.3935 |
| hsa_FNDC3B_0016200 | Intron-Exon-Intron | chr3:171965323-171972875 | chr3:172247533-172255085 | 244 nt | 0.5164 |
| hsa_FNDC3B_0016300 | Intron-Exon-Intron | chr3:171965323-171975230 | chr3:172247533-172257440 | 344 nt | 0.4738 |
| hsa_FNDC3B_0015400 | Intron-Exon-Intron | chr3:171965323-171980628 | chr3:172247533-172262838 | 250 nt | 0.4160 |
| hsa_FNDC3B_0016400 | Intron-Exon-Intron | chr3:171965323-171983158 | chr3:172247533-172265368 | 301 nt | 0.4817 |
| hsa_FNDC3B_0015500 | Intron-Exon-Intron | chr3:171965323-171985507 | chr3:172247533-172267717 | 250 nt | 0.3560 |
Showing 201 to 210 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].