Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0016500 Exon-Exon chr3:171965323-172013304 chr3:172247533-172295514 244 nt 0.5164
hsa_FNDC3B_0016600 Exon-Exon chr3:171965323-172025291 chr3:172247533-172307501 244 nt 0.5164
hsa_FNDC3B_0016000 Exon-Exon chr3:171965323-172062048 chr3:172247533-172344258 1986 nt 0.4955
hsa_FNDC3B_0015600 Exon-Exon chr3:171965323-172070873 chr3:172247533-172353083 2531 nt 0.4966
hsa_FNDC3B_0015700 Exon-Exon chr3:171965323-172080635 chr3:172247533-172362845 2744 nt 0.4942
hsa_FNDC3B_0016700 Exon-Exon chr3:171965323-172098883 chr3:172247533-172381093 128 nt 0.4063
hsa_chr3_0367100 Intergenic-Intergenic chr3:171965418-171969077 chr3:172247628-172251287 177 nt 0.4463
hsa_FNDC3B_0018000 Exon-Exon chr3:171969050-172003774 chr3:172251260-172285984 341 nt 0.4809
hsa_FNDC3B_0018100 Exon-Exon chr3:171969050-172013304 chr3:172251260-172295514 152 nt 0.4737
hsa_FNDC3B_0017800 Intron-Exon-Intron chr3:171969050-172018859 chr3:172251260-172301069 2835 nt 0.3760
Showing 211 to 220 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].