Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0018200 Intron-Exon-Intron chr3:171969050-172037835 chr3:172251260-172320045 199 nt 0.4874
hsa_FNDC3B_0018300 Exon-Exon chr3:171969050-172055191 chr3:172251260-172337401 78 nt 0.3846
hsa_FNDC3B_0017900 Exon-Exon chr3:171969050-172065151 chr3:172251260-172347361 2006 nt 0.4880
hsa_FNDC3B_0018400 Exon-Exon chr3:171969189-172028671 chr3:172251399-172310881 54 nt 0.4259
hsa_FNDC3B_0018500 Exon-Exon chr3:171969261-172013304 chr3:172251471-172295514 130 nt 0.4462
hsa_FNDC3B_0018600 Intron-Intron chr3:171969884-171970101 chr3:172252094-172252311 218 nt 0.3670
hsa_FNDC3B_0018700 Intron-Intron chr3:171969943-171970105 chr3:172252153-172252315 163 nt 0.3620
hsa_chr3_0367300 Intergenic-Intergenic chr3:171972498-171973061 chr3:172254708-172255271 564 nt 0.4078
hsa_FNDC3B_0018800 Intron-Intron chr3:171974979-171996440 chr3:172257189-172278650 250 nt 0.3280
hsa_FNDC3B_0018900 Intron-Intron chr3:171976850-171979873 chr3:172259060-172262083 250 nt 0.2760
Showing 221 to 230 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].