Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_FNDC3B_0019100 | Intron-Intron | chr3:171979659-171980628 | chr3:172261869-172262838 | 436 nt | 0.4587 |
| hsa_FNDC3B_0019200 | Intron-Intron | chr3:171979659-171983158 | chr3:172261869-172265368 | 57 nt | 0.3333 |
| hsa_FNDC3B_0019300 | Intron-Exon-Intron | chr3:171979659-172003774 | chr3:172261869-172285984 | 274 nt | 0.4197 |
| hsa_FNDC3B_0019000 | Intron-Exon-Intron | chr3:171979659-172016577 | chr3:172261869-172298787 | 250 nt | 0.3280 |
| hsa_FNDC3B_0019400 | Intron-Exon-Intron | chr3:171979659-172028671 | chr3:172261869-172310881 | 193 nt | 0.5078 |
| hsa_chr3_0367500 | Intergenic-Intergenic | chr3:171994292-171994439 | chr3:172276502-172276649 | 148 nt | 0.3716 |
| hsa_FNDC3B_0019500 | Intron-Exon-Intron | chr3:172000699-172013304 | chr3:172282909-172295514 | 61 nt | 0.5246 |
| hsa_FNDC3B_0019600 | Intron-Exon-Intron | chr3:172002145-172028671 | chr3:172284355-172310881 | 193 nt | 0.5078 |
| hsa_FNDC3B_0019700 | Intron-Exon-Intron | chr3:172003220-172003774 | chr3:172285430-172285984 | 555 nt | 0.3838 |
| hsa_FNDC3B_0020100 | Exon-Exon | chr3:172003716-172013304 | chr3:172285926-172295514 | 211 nt | 0.4550 |
Showing 231 to 240 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].