Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0020300 Exon-Exon chr3:172003716-172025291 chr3:172285926-172307501 59 nt 0.4068
hsa_FNDC3B_0020200 Exon-Exon chr3:172003716-172048505 chr3:172285926-172330715 764 nt 0.4791
hsa_FNDC3B_0020400 Exon-Exon chr3:172003716-172055191 chr3:172285926-172337401 72 nt 0.4167
hsa_FNDC3B_0020000 Exon-Exon chr3:172003716-172070873 chr3:172285926-172353083 2005 nt 0.4943
hsa_FNDC3B_0020500 Exon-Exon chr3:172003716-172098883 chr3:172285926-172381093 59 nt 0.4068
hsa_FNDC3B_0020600 Exon-Exon chr3:172003738-172016577 chr3:172285948-172298787 37 nt 0.4595
hsa_chr3_0367700 Intergenic-Intergenic chr3:172007256-172007426 chr3:172289466-172289636 171 nt 0.3977
hsa_chr3_0367800 Intergenic-Intergenic chr3:172007454-172007650 chr3:172289664-172289860 197 nt 0.5584
hsa_FNDC3B_0020700 Intron-Intron chr3:172010244-172010946 chr3:172292454-172293156 703 nt 0.4026
hsa_FNDC3B_0021000 Exon-Exon chr3:172013153-172016577 chr3:172295363-172298787 152 nt 0.4737
Showing 241 to 250 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].