Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0022500 Exon-Exon chr3:172025153-172070873 chr3:172307363-172353083 1734 nt 0.5035
hsa_FNDC3B_0022800 Exon-Exon chr3:172025232-172064230 chr3:172307442-172346440 1224 nt 0.4984
hsa_FNDC3B_0022900 Exon-Exon chr3:172028618-172048505 chr3:172310828-172330715 354 nt 0.4887
hsa_FNDC3B_0023100 Exon-Exon chr3:172028618-172050965 chr3:172310828-172333175 141 nt 0.3901
hsa_FNDC3B_0023000 Exon-Exon chr3:172028618-172064230 chr3:172310828-172346440 1164 nt 0.4974
hsa_chr3_0367900 Intergenic-Intergenic chr3:172028622-172070722 chr3:172310832-172352932 330 nt 0.5030
hsa_chr3_0368000 Intergenic-Intergenic chr3:172030548-172032618 chr3:172312758-172314828 2071 nt 0.4442
hsa_FNDC3B_0023200 Intron-Intron chr3:172034027-172037942 chr3:172316237-172320152 250 nt 0.4400
hsa_chr3_0368100 Intergenic-Intergenic chr3:172044751-172045044 chr3:172326961-172327254 294 nt 0.4558
hsa_FNDC3B_0023400 Exon-Exon chr3:172046742-172048505 chr3:172328952-172330715 300 nt 0.5000
Showing 261 to 270 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].