Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0024400 Exon-Exon chr3:172050879-172055191 chr3:172333089-172337401 72 nt 0.4167
hsa_FNDC3B_0024500 Exon-Exon chr3:172050879-172065151 chr3:172333089-172347361 150 nt 0.4467
hsa_FNDC3B_0024800 Exon-Exon chr3:172053314-172053449 chr3:172335524-172335659 136 nt 0.2941
hsa_FNDC3B_0024900 Exon-Exon chr3:172055120-172064230 chr3:172337330-172346440 584 nt 0.5223
hsa_chr3_0368400 Intergenic-Intergenic chr3:172058325-172058545 chr3:172340535-172340755 221 nt 0.5113
hsa_FNDC3B_0025100 Exon-Exon chr3:172060801-172065151 chr3:172343011-172347361 543 nt 0.5083
hsa_FNDC3B_0025200 Exon-Exon chr3:172060801-172070873 chr3:172343011-172353083 824 nt 0.5194
hsa_chr3_0368500 Intergenic-Intergenic chr3:172061995-172065122 chr3:172344205-172347332 54 nt 0.5926
hsa_FNDC3B_0025400 Intron-Exon chr3:172063360-172064218 chr3:172345570-172346428 859 nt 0.3737
hsa_chr3_0368600 Intergenic-Intergenic chr3:172063462-172063944 chr3:172345672-172346154 483 nt 0.3602
Showing 281 to 290 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].