Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0010100 Exon-Exon chr3:171851261-171944737 chr3:172133471-172226947 153 nt 0.4510
hsa_FNDC3B_0010200 Exon-Exon chr3:171851261-171969331 chr3:172133471-172251541 679 nt 0.4934
hsa_FNDC3B_0010300 Exon-Exon chr3:171851261-172070873 chr3:172133471-172353083 2684 nt 0.4940
hsa_chr3_0366700 Intergenic-Intergenic chr3:171889866-171890059 chr3:172172076-172172269 194 nt 0.3918
hsa_FNDC3B_0012600 Exon-Exon chr3:171944661-171944737 chr3:172226871-172226947 77 nt 0.4935
hsa_FNDC3B_0012700 Exon-Exon chr3:171944661-171965566 chr3:172226871-172247776 321 nt 0.5109
hsa_FNDC3B_0012800 Exon-Exon chr3:171944661-171969331 chr3:172226871-172251541 603 nt 0.5041
hsa_FNDC3B_0012900 Exon-Exon chr3:171944661-172016577 chr3:172226871-172298787 874 nt 0.4828
hsa_FNDC3B_0013000 Exon-Exon chr3:171944661-172028671 chr3:172226871-172310881 1067 nt 0.4873
hsa_FNDC3B_0014800 Exon-Exon chr3:171965323-171969331 chr3:172247533-172251541 526 nt 0.5057
Showing 21 to 30 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].