Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0025700 Exon-Exon chr3:172064117-172065151 chr3:172346327-172347361 120 nt 0.4750
hsa_FNDC3B_0025500 Exon-Exon chr3:172064117-172070873 chr3:172346327-172353083 545 nt 0.5009
hsa_FNDC3B_0025800 Exon-Exon chr3:172064117-172080635 chr3:172346327-172362845 114 nt 0.4737
hsa_FNDC3B_0025900 Exon-Exon chr3:172064117-172098883 chr3:172346327-172381093 114 nt 0.4737
hsa_FNDC3B_0025600 Exon-Exon chr3:172064117-172115282 chr3:172346327-172397492 1382 nt 0.4783
hsa_chr3_0368700 Intergenic-Intergenic chr3:172064184-172070722 chr3:172346394-172352932 47 nt 0.4468
hsa_chr3_0368800 Intergenic-Intergenic chr3:172064184-172070867 chr3:172346394-172353077 472 nt 0.5000
hsa_FNDC3B_0026000 Exon-Exon chr3:172065002-172070873 chr3:172347212-172353083 150 nt 0.4467
hsa_FNDC3B_0026100 Exon-Exon chr3:172065002-172098883 chr3:172347212-172381093 150 nt 0.4467
hsa_FNDC3B_0026200 Intron-Intron chr3:172066985-172067540 chr3:172349195-172349750 556 nt 0.3597
Showing 291 to 300 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].