Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0026500 Exon-Exon chr3:172070593-172080635 chr3:172352803-172362845 494 nt 0.5081
hsa_FNDC3B_0026600 Exon-Exon chr3:172070593-172098883 chr3:172352803-172381093 789 nt 0.4918
hsa_chr3_0368900 Intergenic-Intergenic chr3:172070623-172096188 chr3:172352833-172378398 593 nt 0.5008
hsa_chr3_0369000 Intergenic-Intergenic chr3:172070832-172096092 chr3:172353042-172378302 75 nt 0.4533
hsa_chr3_0369100 Intergenic-Intergenic chr3:172073540-172074662 chr3:172355750-172356872 1123 nt 0.4194
hsa_FNDC3B_0026800 Exon-Exon chr3:172080423-172096226 chr3:172362633-172378436 380 nt 0.4842
hsa_FNDC3B_0026900 Exon-Exon chr3:172080516-172098883 chr3:172362726-172381093 415 nt 0.4747
hsa_chr3_0369200 Intergenic-Intergenic chr3:172080607-172115009 chr3:172362817-172397219 196 nt 0.5051
hsa_chr3_0369300 Intergenic-Intergenic chr3:172081393-172081631 chr3:172363603-172363841 239 nt 0.4477
hsa_FNDC3B_0027000 Intron-Intron chr3:172087860-172088007 chr3:172370070-172370217 148 nt 0.3243
Showing 301 to 310 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].