Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0027100 Intron-Intron chr3:172090508-172090777 chr3:172372718-172372987 270 nt 0.4778
hsa_FNDC3B_0027200 Exon-Exon chr3:172096060-172096226 chr3:172378270-172378436 167 nt 0.5090
hsa_FNDC3B_0027300 Exon-Exon chr3:172096060-172098883 chr3:172378270-172381093 128 nt 0.4063
hsa_FNDC3B_0027400 Exon-Exon chr3:172096100-172115112 chr3:172378310-172397322 414 nt 0.4903
hsa_FNDC3B_0027500 Intron-Intron chr3:172105394-172105592 chr3:172387604-172387802 199 nt 0.3920
hsa_FNDC3B_0027600 Intron-Intron chr3:172108520-172108868 chr3:172390730-172391078 349 nt 0.4556
hsa_FNDC3B_0027700 Intron-Intron chr3:172110271-172110484 chr3:172392481-172392694 214 nt 0.4252
hsa_chr3_0369400 Intergenic-Intergenic chr3:172115931-172116181 chr3:172398141-172398391 251 nt 0.3227
hsa_FNDC3B_0027800 Exon-Exon chr3:172116347-172116603 chr3:172398557-172398813 257 nt 0.4280
hsa_FNDC3B_0027900 Exon-Exon chr3:172116741-172116985 chr3:172398951-172399195 245 nt 0.3265
Showing 311 to 320 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].