Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0017300 Exon-Exon chr3:171969050-172046866 chr3:172251260-172329076 871 nt 0.4811
hsa_FNDC3B_0017400 Exon-Exon chr3:171969050-172052872 chr3:172251260-172335082 1272 nt 0.4772
hsa_FNDC3B_0017500 Exon-Exon chr3:171969050-172064230 chr3:172251260-172346440 1856 nt 0.4914
hsa_FNDC3B_0017600 Exon-Exon chr3:171969050-172070873 chr3:172251260-172353083 2287 nt 0.4945
hsa_FNDC3B_0017700 Exon-Exon chr3:171969050-172098883 chr3:172251260-172381093 2795 nt 0.4891
hsa_FNDC3B_0019800 Exon-Exon chr3:172003716-172016577 chr3:172285926-172298787 271 nt 0.4354
hsa_FNDC3B_0019900 Exon-Exon chr3:172003716-172028671 chr3:172285926-172310881 464 nt 0.4655
hsa_FNDC3B_0020800 Exon-Exon chr3:172013153-172028671 chr3:172295363-172310881 405 nt 0.4741
hsa_FNDC3B_0021600 Exon-Exon chr3:172016518-172028671 chr3:172298728-172310881 253 nt 0.4743
hsa_FNDC3B_0021700 Exon-Exon chr3:172016518-172052872 chr3:172298728-172335082 779 nt 0.4763
Showing 41 to 50 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].