Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0021900 Exon-Exon chr3:172025153-172025291 chr3:172307363-172307501 139 nt 0.5396
hsa_FNDC3B_0022000 Exon-Exon chr3:172025153-172046866 chr3:172307363-172329076 318 nt 0.5063
hsa_FNDC3B_0022100 Exon-Exon chr3:172025153-172059021 chr3:172307363-172341231 910 nt 0.4890
hsa_FNDC3B_0022200 Exon-Exon chr3:172025153-172064230 chr3:172307363-172346440 1303 nt 0.5019
hsa_FNDC3B_0022300 Exon-Exon chr3:172025153-172098883 chr3:172307363-172381093 2242 nt 0.4946
hsa_FNDC3B_0023300 Exon-Exon chr3:172046742-172062048 chr3:172328952-172344258 996 nt 0.5040
hsa_FNDC3B_0024300 Exon-Exon chr3:172050879-172064230 chr3:172333089-172346440 810 nt 0.5012
hsa_FNDC3B_0024600 Exon-Exon chr3:172052734-172062048 chr3:172334944-172344258 609 nt 0.5255
hsa_FNDC3B_0024700 Exon-Exon chr3:172052734-172070873 chr3:172334944-172353083 1154 nt 0.5139
hsa_FNDC3B_0025000 Exon-Exon chr3:172058903-172118492 chr3:172341113-172400702 250 nt 0.3080
Showing 51 to 60 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].