Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0025300 Exon-Exon chr3:172061876-172062048 chr3:172344086-172344258 173 nt 0.5896
hsa_FNDC3B_0026300 Exon-Exon chr3:172070593-172070873 chr3:172352803-172353083 281 nt 0.5409
hsa_FNDC3B_0026400 Exon-Exon chr3:172070593-172096226 chr3:172352803-172378436 661 nt 0.5083
hsa_FNDC3B_0026700 Exon-Exon chr3:172080423-172098883 chr3:172362633-172381093 508 nt 0.4646
hsa_AC092964.1_0000100 Intron-Intron chr3:172037696-172038111 chr3:172319906-172320321 416 nt 0.5192
hsa_FNDC3B_0000600 Exon-Exon chr3:171757440-171830380 chr3:172039650-172112590 79 nt 0.7848
hsa_FNDC3B_0000700 Exon-Exon chr3:171757445-171830335 chr3:172039655-172112545 94 nt 0.5000
hsa_FNDC3B_0000800 Exon-Exon chr3:171757463-171830380 chr3:172039673-172112590 238 nt 0.6092
hsa_chr3_0364800 Intergenic-Intergenic chr3:171759705-171820860 chr3:172041915-172103070 250 nt 0.3440
hsa_FNDC3B_0001300 Intron-Exon-Intron chr3:171761602-171851336 chr3:172043812-172133546 250 nt 0.3000
Showing 61 to 70 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].