Basic Information

Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B FAD104 YVTM2421 PRO4979 Fibronectin Type III Domain-Containing Protein 3B Factor For Adipocyte Differentiation 104 HCV NS5A-Binding Protein 37 DKFZp762K137 FLJ23399 NS5ABP37
Location (GRCh37)
3:171757418-172118492 UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
UCSC Genome Browser Search in Marker Scope
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_FNDC3B_0001400 Intron-Intron chr3:171763026-171763269 chr3:172045236-172045479 244 nt 0.4344
hsa_FNDC3B_0001500 Intron-Intron chr3:171763835-171764641 chr3:172046045-172046851 807 nt 0.3928
hsa_FNDC3B_0001600 Intron-Exon-Intron chr3:171764698-171851336 chr3:172046908-172133546 255 nt 0.4824
hsa_FNDC3B_0001700 Intron-Intron chr3:171766698-171767041 chr3:172048908-172049251 344 nt 0.3488
hsa_FNDC3B_0001800 Intron-Exon-Intron chr3:171767888-171851336 chr3:172050098-172133546 76 nt 0.4079
hsa_FNDC3B_0001900 Intron-Intron chr3:171768438-171782583 chr3:172050648-172064793 250 nt 0.3200
hsa_chr3_0364900 Intergenic-Intergenic chr3:171769579-171770606 chr3:172051789-172052816 1028 nt 0.4232
hsa_chr3_0365000 Intergenic-Intergenic chr3:171770117-171770462 chr3:172052327-172052672 346 nt 0.4798
hsa_FNDC3B_0002000 Intron-Intron chr3:171770444-171770616 chr3:172052654-172052826 173 nt 0.4682
hsa_chr3_0365100 Intergenic-Intergenic chr3:171771901-171775194 chr3:172054111-172057404 250 nt 0.3200
Showing 71 to 80 of 320 entries
Forensic Context

A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].