Basic Information
Symbol
circFNDC3B
RNA Class
circRNA
Alias
Fibronectin Type III Domain Containing 3B
FAD104
YVTM2421
PRO4979
Fibronectin Type III Domain-Containing Protein 3B
Factor For Adipocyte Differentiation 104
HCV NS5A-Binding Protein 37
DKFZp762K137
FLJ23399
NS5ABP37
Location (GRCh37)
3:171757418-172118492
UCSC Genome Browser
Location (GRCh38)
3:172039628-172400702
Host gene
FNDC3B
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr3_0365200 | Intergenic-Intergenic | chr3:171771997-171772563 | chr3:172054207-172054773 | 567 nt | 0.5009 |
| hsa_FNDC3B_0002100 | Intron-Exon-Intron | chr3:171772367-171830380 | chr3:172054577-172112590 | 250 nt | 0.3960 |
| hsa_FNDC3B_0002200 | Intron-Exon-Intron | chr3:171772367-171851336 | chr3:172054577-172133546 | 137 nt | 0.4234 |
| hsa_FNDC3B_0002300 | Intron-Exon-Intron | chr3:171772367-171969331 | chr3:172054577-172251541 | 61 nt | 0.4426 |
| hsa_FNDC3B_0002400 | Intron-Exon-Intron | chr3:171778500-171830380 | chr3:172060710-172112590 | 242 nt | 0.4711 |
| hsa_FNDC3B_0002500 | Intron-Exon-Intron | chr3:171778500-171851336 | chr3:172060710-172133546 | 318 nt | 0.4560 |
| hsa_FNDC3B_0002600 | Intron-Exon-Intron | chr3:171778500-171944737 | chr3:172060710-172226947 | 180 nt | 0.4444 |
| hsa_FNDC3B_0002700 | Intron-Exon-Intron | chr3:171778500-171969331 | chr3:172060710-172251541 | 242 nt | 0.4711 |
| hsa_FNDC3B_0002800 | Intron-Intron | chr3:171778527-171778803 | chr3:172060737-172061013 | 277 nt | 0.3069 |
| hsa_FNDC3B_0002900 | Intron-Intron | chr3:171778667-171778881 | chr3:172060877-172061091 | 215 nt | 0.3860 |
Showing 81 to 90 of 320 entries
Forensic Context
A study in mice demonstrated that the circFNDC3B was significantly downregulated in hearts post-myocardial infarction and in human cardiac tissues of ischemic cardiomyopathy patients, where its overexpression in cardiac endothelial cells increased vascular endothelial growth factor expression, enhanced angiogenic activity, and reduced apoptosis [Tian et al. DOI:10.3390/molecules26041155].