Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0001200 | Exon-Exon | chr1:243666012-243666150 | chr1:243502710-243502848 | 139 nt | 0.5396 |
| hsa_AKT3_0001700 | Exon-Exon | chr1:243667690-243736350 | chr1:243504388-243573048 | 1605 nt | 0.4050 |
| hsa_AKT3_0002200 | Exon-Exon | chr1:243668234-243668458 | chr1:243504932-243505156 | 225 nt | 0.4400 |
| hsa_chr1_0714600 | Intergenic-Intergenic | chr1:243673801-243674014 | chr1:243510499-243510712 | 214 nt | 0.5234 |
| hsa_AKT3_0002300 | Exon-Exon | chr1:243675626-243727150 | chr1:243512324-243563848 | 535 nt | 0.3925 |
| hsa_AKT3_0002400 | Exon-Exon | chr1:243675626-243736350 | chr1:243512324-243573048 | 658 nt | 0.4073 |
| hsa_AKT3_0003800 | Exon-Exon | chr1:243708812-243727150 | chr1:243545510-243563848 | 432 nt | 0.4074 |
| hsa_AKT3_0003900 | Intron-Exon-Intron | chr1:243708812-243727689 | chr1:243545510-243564387 | 971 nt | 0.3471 |
| hsa_AKT3_0004000 | Exon-Exon | chr1:243708812-243736350 | chr1:243545510-243573048 | 555 nt | 0.4216 |
| hsa_AKT3_0004100 | Exon-Exon | chr1:243708812-243778463 | chr1:243545510-243615161 | 690 nt | 0.4159 |
Showing 1 to 10 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].