Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr1_0714900 | Intergenic-Intergenic | chr1:243694529-243697061 | chr1:243531227-243533759 | 2533 nt | 0.3368 |
| hsa_AKT3_0003700 | Intron-Exon-Intron | chr1:243707764-243736350 | chr1:243544462-243573048 | 1603 nt | 0.3880 |
| hsa_AKT3_0004700 | Exon-Exon | chr1:243708812-243716245 | chr1:243545510-243552943 | 88 nt | 0.3864 |
| hsa_AKT3_0004800 | Intron-Exon-Intron | chr1:243708812-243716392 | chr1:243545510-243553090 | 88 nt | 0.3864 |
| hsa_AKT3_0004900 | Intron-Exon-Intron | chr1:243708812-243730176 | chr1:243545510-243566874 | 97 nt | 0.2784 |
| hsa_AKT3_0005000 | Intron-Exon-Intron | chr1:243708812-243751295 | chr1:243545510-243587993 | 114 nt | 0.3772 |
| hsa_AKT3_0005100 | Exon-Exon | chr1:243708812-243777041 | chr1:243545510-243613739 | 211 nt | 0.4360 |
| hsa_AKT3_0005200 | Exon-Exon | chr1:243708812-243801010 | chr1:243545510-243637708 | 321 nt | 0.3801 |
| hsa_AKT3_0005300 | Intron-Exon-Intron | chr1:243708812-243802593 | chr1:243545510-243639291 | 135 nt | 0.4000 |
| hsa_AKT3_0005400 | Exon-Exon | chr1:243708812-243809339 | chr1:243545510-243646037 | 151 nt | 0.4172 |
Showing 91 to 100 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].