Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0005500 | Exon-Exon | chr1:243708812-243828185 | chr1:243545510-243664883 | 118 nt | 0.3644 |
| hsa_AKT3_0005600 | Intron-Exon-Intron | chr1:243708812-243841362 | chr1:243545510-243678060 | 88 nt | 0.3864 |
| hsa_AKT3_0005700 | Intron-Exon-Intron | chr1:243708812-243846612 | chr1:243545510-243683310 | 114 nt | 0.3684 |
| hsa_AKT3_0005800 | Exon-Exon | chr1:243708812-243858996 | chr1:243545510-243695694 | 88 nt | 0.3864 |
| hsa_AKT3_0005900 | Exon-Exon | chr1:243708812-243859018 | chr1:243545510-243695716 | 541 nt | 0.3863 |
| hsa_AKT3_0006000 | Intron-Exon-Intron | chr1:243708812-243859046 | chr1:243545510-243695744 | 88 nt | 0.3864 |
| hsa_AKT3_0006100 | Intron-Exon-Intron | chr1:243708812-243863520 | chr1:243545510-243700218 | 88 nt | 0.3864 |
| hsa_AKT3_0006200 | Intron-Exon-Intron | chr1:243708812-243873171 | chr1:243545510-243709869 | 207 nt | 0.3623 |
| hsa_AKT3_0004400 | Intron-Exon-Intron | chr1:243708812-243890495 | chr1:243545510-243727193 | 250 nt | 0.3120 |
| hsa_AKT3_0006300 | Intron-Exon-Intron | chr1:243708812-243898392 | chr1:243545510-243735090 | 221 nt | 0.4615 |
Showing 101 to 110 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].