Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0004500 | Intron-Exon-Intron | chr1:243708812-243898402 | chr1:243545510-243735100 | 250 nt | 0.3640 |
| hsa_AKT3_0006400 | Intron-Exon-Intron | chr1:243708812-243898418 | chr1:243545510-243735116 | 303 nt | 0.3960 |
| hsa_AKT3_0006500 | Intron-Exon-Intron | chr1:243708812-243899049 | chr1:243545510-243735747 | 94 nt | 0.3830 |
| hsa_AKT3_0006600 | Intron-Exon-Intron | chr1:243708812-243902915 | chr1:243545510-243739613 | 217 nt | 0.3917 |
| hsa_AKT3_0004600 | Intron-Exon-Intron | chr1:243708812-243904152 | chr1:243545510-243740850 | 250 nt | 0.3120 |
| hsa_AKT3_0006700 | Intron-Exon-Intron | chr1:243708812-243905109 | chr1:243545510-243741807 | 40 nt | 0.4250 |
| hsa_AKT3_0006800 | Intron-Exon-Intron | chr1:243708812-243905345 | chr1:243545510-243742043 | 293 nt | 0.3925 |
| hsa_AKT3_0006900 | Intron-Intron | chr1:243712669-243712818 | chr1:243549367-243549516 | 150 nt | 0.4200 |
| hsa_AKT3_0007300 | Exon-Exon | chr1:243716031-243716245 | chr1:243552729-243552943 | 215 nt | 0.4000 |
| hsa_AKT3_0007400 | Intron-Exon-Intron | chr1:243716031-243716380 | chr1:243552729-243553078 | 350 nt | 0.3343 |
Showing 111 to 120 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].