Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
UCSC Genome Browser Search in Marker Scope
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0007500 Intron-Exon-Intron chr1:243716031-243716392 chr1:243552729-243553090 362 nt 0.3398
hsa_AKT3_0007600 Exon-Exon chr1:243716031-243727150 chr1:243552729-243563848 129 nt 0.4341
hsa_AKT3_0007700 Intron-Exon-Intron chr1:243716031-243727689 chr1:243552729-243564387 215 nt 0.4000
hsa_AKT3_0007800 Exon-Exon chr1:243716031-243809339 chr1:243552729-243646037 145 nt 0.4276
hsa_AKT3_0007900 Exon-Exon chr1:243716031-243828185 chr1:243552729-243664883 118 nt 0.3729
hsa_AKT3_0008000 Exon-Exon chr1:243716031-243859018 chr1:243552729-243695716 244 nt 0.3730
hsa_AKT3_0008100 Intron-Exon-Intron chr1:243716031-243874118 chr1:243552729-243710816 119 nt 0.3697
hsa_AKT3_0008200 Intron-Exon-Intron chr1:243716031-243899049 chr1:243552729-243735747 141 nt 0.4043
hsa_AKT3_0008300 Intron-Exon-Intron chr1:243716031-243902915 chr1:243552729-243739613 91 nt 0.4176
hsa_chr1_0715100 Intergenic-Intergenic chr1:243719009-243719258 chr1:243555707-243555956 250 nt 0.3200
Showing 121 to 130 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].