Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0008400 Intron-Intron chr1:243724838-243724979 chr1:243561536-243561677 142 nt 0.3099
hsa_AKT3_0008500 Intron-Intron chr1:243725072-243725229 chr1:243561770-243561927 158 nt 0.4114
hsa_AKT3_0009200 Intron-Exon-Intron chr1:243727022-243762293 chr1:243563720-243598991 250 nt 0.3080
hsa_AKT3_0009600 Exon-Exon chr1:243727022-243828185 chr1:243563720-243664883 135 nt 0.4370
hsa_AKT3_0009700 Intron-Exon-Intron chr1:243727022-243846612 chr1:243563720-243683310 114 nt 0.3684
hsa_AKT3_0009500 Intron-Exon-Intron chr1:243727022-243859046 chr1:243563720-243695744 930 nt 0.4022
hsa_AKT3_0009800 Intron-Exon-Intron chr1:243727022-243898392 chr1:243563720-243735090 262 nt 0.4733
hsa_AKT3_0009300 Intron-Exon-Intron chr1:243727022-243898402 chr1:243563720-243735100 250 nt 0.3880
hsa_AKT3_0009900 Intron-Exon-Intron chr1:243727022-243898418 chr1:243563720-243735116 159 nt 0.4906
hsa_AKT3_0010000 Intron-Exon-Intron chr1:243727022-243902915 chr1:243563720-243739613 91 nt 0.4176
Showing 131 to 140 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].