Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0010100 Intron-Exon-Intron chr1:243727022-243905345 chr1:243563720-243742043 252 nt 0.4524
hsa_AKT3_0009400 Intron-Exon-Intron chr1:243727022-243911815 chr1:243563720-243748513 250 nt 0.3120
hsa_chr1_0715300 Intergenic-Intergenic chr1:243727855-243728047 chr1:243564553-243564745 193 nt 0.3627
hsa_chr1_0715400 Intergenic-Intergenic chr1:243728636-243729611 chr1:243565334-243566309 976 nt 0.3750
hsa_AKT3_0010800 Intron-Exon-Intron chr1:243736228-243759130 chr1:243572926-243595828 250 nt 0.3840
hsa_AKT3_0011100 Exon-Exon chr1:243736228-243800964 chr1:243572926-243637662 118 nt 0.3475
hsa_AKT3_0011200 Exon-Exon chr1:243736228-243809339 chr1:243572926-243646037 268 nt 0.4478
hsa_AKT3_0010900 Intron-Exon-Intron chr1:243736228-243844474 chr1:243572926-243681172 250 nt 0.3600
hsa_AKT3_0011300 Intron-Exon-Intron chr1:243736228-243898418 chr1:243572926-243735116 189 nt 0.4392
hsa_AKT3_0011000 Intron-Exon-Intron chr1:243736228-243899049 chr1:243572926-243735747 250 nt 0.3520
Showing 141 to 150 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].