Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
UCSC Genome Browser Search in Marker Scope
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0011400 Intron-Exon-Intron chr1:243736228-243902915 chr1:243572926-243739613 97 nt 0.4227
hsa_AKT3_0011500 Intron-Exon-Intron chr1:243736228-243905345 chr1:243572926-243742043 231 nt 0.4069
hsa_AKT3_0011600 Intron-Exon-Intron chr1:243751182-243809339 chr1:243587880-243646037 135 nt 0.3926
hsa_chr1_0715500 Intergenic-Intergenic chr1:243753806-243754372 chr1:243590504-243591070 567 nt 0.3333
hsa_AKT3_0011700 Intron-Intron chr1:243756912-243758126 chr1:243593610-243594824 1215 nt 0.3564
hsa_AKT3_0011800 Intron-Exon-Intron chr1:243762247-243828185 chr1:243598945-243664883 66 nt 0.3788
hsa_chr1_0715600 Intergenic-Intergenic chr1:243764944-243832001 chr1:243601642-243668699 250 nt 0.2840
hsa_AKT3_0011900 Intron-Intron chr1:243766577-243766968 chr1:243603275-243603666 392 nt 0.4388
hsa_AKT3_0012000 Intron-Exon-Intron chr1:243776941-243778463 chr1:243613639-243615161 167 nt 0.3892
hsa_AKT3_0012100 Intron-Exon-Intron chr1:243776941-243859018 chr1:243613639-243695716 167 nt 0.3892
Showing 151 to 160 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].