Basic Information
Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3
PKBG
RAC-Gamma
PRKBG
RAC-Gamma Serine/Threonine-Protein Kinase
RAC-PK-Gamma
EC 2.7.11.1
PKB Gamma
STK-2
V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma)
V-Akt Murine Thymoma Viral Oncogene Homolog 3
RAC-Gamma Serine/Threonine Protein Kinase
Protein Kinase B, Gamma
Protein Kinase B Gamma
Protein Kinase Akt-3
PKB-GAMMA
EC 2.7.11
MPPH2
MPPH
Location (GRCh37)
1:243663039-244007318
UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Wound age identification
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_AKT3_0012900 | Intron-Exon-Intron | chr1:243776973-243846612 | chr1:243613671-243683310 | 354 nt | 0.3644 |
| hsa_AKT3_0013000 | Intron-Exon-Intron | chr1:243776973-243859046 | chr1:243613671-243695744 | 223 nt | 0.3901 |
| hsa_AKT3_0013100 | Intron-Exon-Intron | chr1:243776973-243863520 | chr1:243613671-243700218 | 468 nt | 0.3803 |
| hsa_AKT3_0013200 | Intron-Exon-Intron | chr1:243776973-243872548 | chr1:243613671-243709246 | 69 nt | 0.4058 |
| hsa_AKT3_0013300 | Intron-Exon-Intron | chr1:243776973-243873175 | chr1:243613671-243709873 | 482 nt | 0.3693 |
| hsa_AKT3_0013400 | Intron-Exon-Intron | chr1:243776973-243890495 | chr1:243613671-243727193 | 202 nt | 0.4059 |
| hsa_AKT3_0013500 | Intron-Exon-Intron | chr1:243776973-243898392 | chr1:243613671-243735090 | 133 nt | 0.5113 |
| hsa_AKT3_0013600 | Intron-Exon-Intron | chr1:243776973-243898402 | chr1:243613671-243735100 | 149 nt | 0.5235 |
| hsa_AKT3_0013700 | Intron-Exon-Intron | chr1:243776973-243898418 | chr1:243613671-243735116 | 565 nt | 0.4248 |
| hsa_AKT3_0013800 | Intron-Exon-Intron | chr1:243776973-243899049 | chr1:243613671-243735747 | 75 nt | 0.4000 |
Showing 161 to 170 of 314 entries
Forensic Context
A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].