Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0013900 Intron-Exon-Intron chr1:243776973-243902915 chr1:243613671-243739613 280 nt 0.4107
hsa_AKT3_0014000 Intron-Exon-Intron chr1:243776973-243905345 chr1:243613671-243742043 183 nt 0.4098
hsa_AKT3_0014100 Intron-Exon-Intron chr1:243776973-243952128 chr1:243613671-243788826 69 nt 0.4058
hsa_AKT3_0012800 Intron-Exon-Intron chr1:243776973-243969155 chr1:243613671-243805853 250 nt 0.2920
hsa_AKT3_0014300 Exon-Exon chr1:243778398-243801044 chr1:243615096-243637742 198 nt 0.3485
hsa_AKT3_0014400 Exon-Exon chr1:243778398-243828185 chr1:243615096-243664883 198 nt 0.3485
hsa_AKT3_0014500 Intron-Exon-Intron chr1:243778398-243847246 chr1:243615096-243683944 66 nt 0.3788
hsa_AKT3_0014600 Intron-Exon-Intron chr1:243778398-243899049 chr1:243615096-243735747 66 nt 0.3788
hsa_AKT3_0014700 Intron-Intron chr1:243785062-243785922 chr1:243621760-243622620 861 nt 0.3717
hsa_AKT3_0014800 Intron-Intron chr1:243786962-243787847 chr1:243623660-243624545 886 nt 0.3871
Showing 171 to 180 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].