Basic Information

Symbol
circAKT3
RNA Class
circRNA
Alias
AKT Serine/Threonine Kinase 3 PKBG RAC-Gamma PRKBG RAC-Gamma Serine/Threonine-Protein Kinase RAC-PK-Gamma EC 2.7.11.1 PKB Gamma STK-2 V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) V-Akt Murine Thymoma Viral Oncogene Homolog 3 RAC-Gamma Serine/Threonine Protein Kinase Protein Kinase B, Gamma Protein Kinase B Gamma Protein Kinase Akt-3 PKB-GAMMA EC 2.7.11 MPPH2 MPPH
Location (GRCh37)
1:243663039-244007318 UCSC Genome Browser
Location (GRCh38)
1:243499737-243844016
UCSC Genome Browser Search in Marker Scope
Host gene
AKT3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_AKT3_0014900 Intron-Intron chr1:243787045-243789017 chr1:243623743-243625715 1973 nt 0.4116
hsa_AKT3_0015500 Exon-Exon chr1:243800913-243809334 chr1:243637611-243646032 272 nt 0.3787
hsa_AKT3_0015600 Intron-Exon-Intron chr1:243800913-243846612 chr1:243637611-243683310 132 nt 0.3333
hsa_AKT3_0015700 Intron-Exon-Intron chr1:243800913-243859046 chr1:243637611-243695744 154 nt 0.3831
hsa_AKT3_0015800 Intron-Exon-Intron chr1:243800913-243898402 chr1:243637611-243735100 420 nt 0.4262
hsa_AKT3_0015900 Intron-Exon-Intron chr1:243800913-243898418 chr1:243637611-243735116 138 nt 0.3333
hsa_AKT3_0016000 Intron-Exon-Intron chr1:243800913-243899049 chr1:243637611-243735747 141 nt 0.4043
hsa_AKT3_0016100 Intron-Exon-Intron chr1:243800913-243905345 chr1:243637611-243742043 309 nt 0.3689
hsa_AKT3_0016200 Intron-Exon-Intron chr1:243800913-243991910 chr1:243637611-243828608 138 nt 0.3478
hsa_AKT3_0016400 Intron-Intron chr1:243805129-243805742 chr1:243641827-243642440 614 nt 0.3893
Showing 181 to 190 of 314 entries
Forensic Context

A study in mice demonstrated that the circAKT3 is highly expressed in brain tissue and plays a crucial role in brain development and neurological disorders [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human traumatic brain injury (TBI) brain tissues identified the circAKT3 as a top down-regulated circular RNA, with a fold change of 0.44, and its decreased expression was validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553].